TNF and atherosclerosis: In KEGG pathway enrichment bubble plots, the top 20 enriched pathways were ranked by FDR, including NOD-like receptor signaling pathway, TNF signaling pathway, NF-kappa B signaling pathway, lipid and atherosclerosis, and viral protein interaction with cytokine and cytokine receptor, most of which are directly related to Mφ inflammatory responses (Figure 5C).