Recently, the importance of the response mediated by Th17 lymphocytes in leishmaniasis has been investigated due to its function in eliminating microorganisms through the expression of IL-17A, which is fundamental for the activation and recruitment of neutrophils mediating inflammatory responses, and had its expression increased in the presence of ACMD-03 [57,66,67]. The gene discussed is IL17A; the disease is leishmaniasis.