The four profiles are described as (1) low psychopathology (T1: 67.3%, T2: 62.7%, T3: 72.6%, T4: 68.1%) with low scores on all disorder subscales, (2) primarily internalizing (T1: 20.2%, T2: 27.0%, T3: 17.4%, T4: 15.2%), with higher scores on GAD, SA, SP, and MDD subscales (3) primarily externalizing (T1: 10.6%, T2: 8.0%, T3: 6.5%, T4: 12.9%) with higher scores on ADHD, ODD, and CD subscales, and (4) high psychopathology (T1: 1.9%, T2: 2.7%, T3: 3.0%, T4: 3.4%) with higher scores on all disorder subscales, see Figure 1. This evidence concerns the gene GAD1 and major depressive disorder.