NETs markers (MPO-DNA, histone-DNA, citrullinated histone H3 [CitH3]) were measured in blood samples, and their associations with stroke severity (National Institutes of Health Stroke Scale [NIHSS] score at 24 h post-reperfusion), long-term functional outcome (modified Rankin Scale [mRS] score at 90-day), and final infarct size (5–7 days) were assessed in EVT and heparin + EVT–treated patients using logistic regression, linear regression, and Pearson’s correlation. The gene discussed is MPO; the disease is stroke disorder.