Additionally, we performed univariable analysis on 33 cancer types and found that PTPN23 significantly impacts overall survival (OS) in several cancers, including kidney chromophobe (KICH), sarcoma (SARC), skin cutaneous melanoma (SKCM), thyroid carcinoma (THCA), and uveal melanoma (UVM) (Fig. 7F). The gene discussed is PTPN23; the disease is cancer.