LCN2 and acute kidney injury: In conclusion, NGAL exerts its bacteriostatic effect by binding to siderophores and interfering with iron utilization by bacterial cells – protective function, but also high level informs about acute kidney injury In our study for patients with urosepsis, Lcn-2 levels were a little bit lower (average concentration 2.085 ± 2.24 ng/mL for urosepsis group vs. average concentration 4.37 ± 13.46 ng/mL for the control group with UTI), resulting in a weaker defence against bacteria; sequestration of Fe(III)-enterobactin complex by NGAL was not as efficient.