The RA samples exhibited an increased abundance of five immune cell types, namely monocytes, myeloid dendritic cells, activated myeloid dendritic cells, neutrophils, and activated NK cells, while three immune cell types, specifically activated CD4 + memory T cells, naïve CD4 + T cells, and gamma delta T cells, showed a decreased presence. The gene discussed is CD4; the disease is rheumatoid arthritis.