Incubating PCa cells with SLC‐0111, CAI#1, and CAI#2 for 48 h reduced their ability to upload exogenous lactic acid (Fig. 5C), suggesting that CA IX/XII‐mediated control of extracellular pH homeostasis is important to facilitate the symport lactate/H+. The gene discussed is CA1; the disease is posterior cortical atrophy.