We mined an independent leprosy single-cell RNA-Seq (scRNA-Seq) dataset composed of RR and L-lep skin lesions (GSE151528) (18) and found that IL1B mRNA expression in RR lesions was restricted to myeloid cells, while TNF was expressed by both myeloid and T cells, with higher expression in myeloid cells. The gene discussed is TNF; the disease is leprosy.