ALOX15B and neoplasm: ALOX15B, arachidonate 15‐lipoxygenase type II (15‐LOX‐2), is a crucial ferroptosis‐related lipid‐peroxidising enzyme, which catalyzes stereo‐specific peroxidation of PUFAs to generate a spectrum of bioactive lipid mediators.[44, 45, 46] In line with the effect of ALOX15B on ferroptosis induction, overexpression of ALOX15B exhibits significant anti‐tumor activity in several in vitro and in vivo tumor models, which indicates that ALOX15B may act as a tumor suppressor.