Notably, samples from the responder group exhibited higher expression of immune activation-related genes compared to the nonresponder group, including effector T cells (T-eff), T cell-inflamed, IFN-γ, cytotoxic, cytolytic activity score (CYT), chemokines, angiogenesis (AG), APC co-stimulation (APC co-sti), inflammation promoting (Inflam-pro), T cell co-stimulation (T cell co-sti), parainflammation (parainflam), and tumor-infiltrating lymphocytes (TIL) (Figure 4A). Here, IFNG is linked to neoplasm.