An enlarged T wave in the ECG may suggest ventricular hypertrophy.[24] M‐mode echocardiogram demonstrated that Stx12‐cKO mice exhibited significant decreases in ejection fraction (EF%) and fractional shortening (FS) in Stx12‐cKO mice compared to that of flox‐control (Stx12‐flox) mice (Figure 2g–j). The gene discussed is STX12; the disease is cardiac hypertrophy.