Cntnap2, which is downregulated in the Foxp1± striatum, has been implicated in various neurodevelopmental disorders including autism.[53] Another point in favor of neuroinflammation is the upregulation of Akt and Pten and the downregulation of Gpr34 in the Foxp1± striatum. The gene discussed is AKT1; the disease is neurodevelopmental disorder.