1. Mediating the Degradation of SAMHD1 to Enhance Infection (Hrecka et al., 2011; Laguette et al., 2011; Zhang et al., 2021; Hofmann et al., 2013)2. Mediating the Degradation of APOBEC3G to Enhance Infection (Yu et al., 2003; Liu et al., 2005)3. Mediating the Degradation of UNG2 to Enhance Infection (Nekorchuk et al., 2013). The gene discussed is SAMHD1; the disease is infection.