The Che team’s research found that KRT6A acts downstream of LSD1 to promote the proliferation and invasion of NSCLC cells (105) In addition, highly expressed KRT6A in LUAD can promote the proliferation and metastasis of lung cancer through EMT and cancer stem cell transformation (106), and can also promote the radioresistance, invasion, and metastasis of lung cancer through the p53 signaling pathway (107). This evidence concerns the gene TP53 and lung cancer.