It has been demonstrated that electroacupuncture at CV12 can significantly increase peripheral β-endorphin levels, promote insulin secretion and release, and effectively relieve hyperglycemia; at the same time, electroacupuncture can change the endocrine function of the hypothalamus, correct blood sugar disorders by affecting the hypothalamic-pituitary-adrenal axis, and thus regulate abnormal endocrine metabolism (48). Here, INS is linked to Hyperglycemia.