In vivo studies involving MiaPaCa2 and PANC1 xenografts revealed that UA treatment significantly inhibited tumor growth (MiaPaCa2: ~ 200 mm3 vs. control ~800 mm3 and PANC1: ~ 200 mm3 vs. control ~850 mm3), reduced proliferation, and induced apoptosis (cleaved Caspase-3) without toxicity. Here, CASP3 is linked to neoplasm.