It has been shown that the distribution of a single nucleotide polymorphism (cSNP) locus (e.g., T418M) of KCNA7 in the normal population adheres to Hardy-Weinberg equilibrium, with no significant difference between the gene frequency and genotype frequency of the locus in patients with non-insulin-dependent diabetes mellitus and healthy controls (36). Here, KCNA7 is linked to type 1 diabetes mellitus.