Cytokine profiling analysis of plasma from mice bearing T12 tumors post combination treatment revealed an increase in the levels of the pro T and NK cell stimulant IL-5 (27),(28),(29) type II interferon response, INF-y (30),(31), pro-inflammatory macrophage marker MIG (CXCL9) (32),(33) and anti-tumor response IL-4 (34) (Figure 1K, S2E and Supplementary table S12). The gene discussed is IL4; the disease is neoplasm.