While there has been speculation that the lymphocyte cuff observed in Mtb granulomas is due to exclusion from the core, we found clear induction of Cxcl13, which guides B cells into secondary lymphoid follicles, in the region of the cuff, suggesting that lymphocytes may be actively recruited to the ring rather than excluded from the center44. Here, CXCL13 is linked to Granuloma.