We transfected two independent siRNA oligonucleotides against SRSF3 (11), along with a control siRNA, into four NSCLC cell lines: A549 (no TK mutation; TP53 wild-type), NCI-H1975 (EGFR L858R/T790M; TP53 R273H mutant), NCI-H322 (no TK mutation; TP53 R248L mutant) and NCI-H596 (no TK mutation; TP53 G245C mutant) (Table 1). Here, EGFR is linked to non-small cell lung carcinoma.