To identify candidate factors that may mediate the SRSF3 knockdown-induced senescence in NSCLC cells, we first compared two RNA-sequence data previously published: differentially expressed genes (DEGs) in NSCLC tissues versus matched non-tumor lung tissues (19); and DEGs associated with SRSF3 inhibition in two glioma stem-like cells (13). The gene discussed is SRSF3; the disease is glioma.