Key pathways include Endocytosis (oas04144, PDGFRA, RABEP1, ARAP2, EPS15L1, RAB11FIP4), Toll-like receptor signaling (oas04620, MAP2K3, TICAM1, LY96), Cell cycle (oas04110, CCNB2, CDC6, RAD21), Cellular senescence (oas04218, MAP2K3, CCNB2, ITPR1), Pertussis (oas05133, LY96, TICAM1), Focal adhesion (oas04510, ITGA1, PDGFRA, FLNC), PD-L1 expression and PD-1 checkpoint pathway in cancer (oas05235, MAP2K3, TICAM1) and Proteoglycans in cancer (oas05205, FLNC, IQGAP1, ITPR1). The gene discussed is PDGFRA; the disease is pertussis.