S100A11 and malignant colon neoplasm: In addition, analysis of the proportion of immune cell subpopulations showed that S100A11 expression was associated with a higher proportion of neutrophils and a lower proportion of regulatory T cells (Figure 6G), suggesting that S100A11 may affect the balance of immune cell subpopulations in the tumor microenvironment, which may lead to immune evasion by colon cancer cells.