In addition, analysis of the proportion of immune cell subpopulations showed that S100A11 expression was associated with a higher proportion of neutrophils and a lower proportion of regulatory T cells (Figure 6G), suggesting that S100A11 may affect the balance of immune cell subpopulations in the tumor microenvironment, which may lead to immune evasion by colon cancer cells. The gene discussed is S100A11; the disease is neoplasm.