Compared to the model group, BBR significantly reduced NLRP3 levels in renal fibrosis animals (Sample size: 52; SMD = −2.77 (95% CI: −3.57 to −1.97), P = 0.241; χ2 = 2.84, I2 = 29.6%). This evidence concerns the gene NLRP3 and renal fibrosis.