Notably, either the oxygen species absorber Pyrogallol or the inhibitor GSK2795039 significantly attenuated the stimulatory effect of STOX1‐A overexpression on the expression levels of the oxygenized PTEN and p‐AKT1 (Ser473) in HCC cells, but had no significant influence on total PTEN and AKT1 expression (Figure 6H), as well as the growth of STOX1‐A overexpressing HCC cells (Figure S3A). This evidence concerns the gene PTEN and hepatocellular carcinoma.