Methyltransferase-like 14 (METTL14), the key writers of m6A modification, upregulates the expression of pinpointed ankyrin repeat domain 22 (ANKRD22) and may promote lipid metabolism reprogramming in NPC cells by interacting with SLC25A1 on mitochondria, thereby supporting the growth of NPC [41] In our study, we observed a significant downregulation of CDS1 in NPC. Here, NPC1 is linked to nasopharyngeal carcinoma.