CCND1 and acute myeloid leukemia: Though a role for Gal-3 as a positive regulator of β-catenin is well recognized [107,108,109,134,135,136], it is currently unclear how Gal-3 might induce the transcription of β-catenin target genes, such as Myc and cyclin D1 in BM-MSCs from patients with AML, since β-catenin was phosphorylated at S33/S37/T41.