FLT3 and acute myeloid leukemia: Higher LGALS3 mRNA expression was strongly related to older age, AML French-American-British (FAB) M4/M5 subtypes, leukemic CD14 expression and PTPN11 mutation, while it was negatively associated with FAB AML M1 subtype, blast counts, serum lactate dehydrogenase (LDH), FLT3-ITD and CEBPA mutations [8].