Gal-3 protein in AML-derived MSCs showed a positive correlation with the expression of thirteen proteins, including p-CTNNB1 (S33/S37/T41), Myc, CCND1 (cyclin D1), MAPK9, BAD, AKT2, CDK4, STAT1 and EGFR, while it negatively correlated with the expression of six proteins, including ITGB3, STMN1, LYN, and SIRT1. The gene discussed is ITGB3; the disease is acute myeloid leukemia.