Furthermore, it reduced liver inflammation (e.g., infiltrates of macrophages), fibrosis (e.g., collagen deposition), biomarkers of liver disease (AST, ALT, bilirubin), and markers of inflammation and fibrosis at mRNA and protein levels [e.g., IL6, collagen, TGF-β3, snail family transcriptional repressor 2 (SNAI2)] [160]. This evidence concerns the gene SNAI2 and liver disorder.