Tyrosine, on the other hand, was included based on multiple lines of relevance: it is a listed drug associated with the SLC3A2 gene in the GeneCards database (https://www.genecards.org/cgi-bin/carddisp.pl?gene=SLC3A2 (accessed on 28 August 2023)), and it is a known physiological substrate of the SLC3A2–LAT1 (SLC7A5) heterodimer, a transporter complex frequently overexpressed in cancer. This evidence concerns the gene SLC7A5 and cancer.