In addition, in the NHANES III cohort including 14,543 participants, it was observed that the dietary fiber intake was negatively associated with serum C-reactive protein (CRP) levels, such that each 10 g/day increase in the total fiber intake was associated with an 11% and 38% decline in the odds of elevated serum CRP levels in the CKD and non-CKD groups, respectively [51]. The gene discussed is CRP; the disease is chronic kidney disease.