MIP-1β, by exerting a chemoattractive effect on inflamed tissues in cells of the immune system, such as monocytes, macrophages, natural killer (NK) cells, and dendritic cells, mobilizes an increase in the circulating quantity of these cells and exacerbates the inflammatory response, causing damage to patients with CKD [51,52]. The gene discussed is CCL4; the disease is chronic kidney disease.