It promotes the activation of nuclear factor kB (NF-κB), a transcription factor that regulates the synthesis of inflammatory cytokines, such as several interleukins (IL-1, IL-6, IL-8, IL-1β, IL-18), tumor necrosis factor-α (TNF-α), interferon-γ (INF-γ), and other molecules, such as vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1), all of which are closely linked to the progression of cardiovascular diseases [4,5,6]. The gene discussed is TNF; the disease is cardiovascular disorder.