Also, in men with T2D not taking insulin, IRs were not significantly different (IR hip: 4.6; 95% CI 2.6–8.0), compared to those using insulin (IR hip: 11.5; 95% CI 6.2–21.4) and men without T2D (IR hip: 6.3; 95% CI 5.5–7.1) for all three fracture types [30]. The gene discussed is INS; the disease is type 2 diabetes mellitus.