In the IA PJI cohort, authors showed a low-to-moderate diagnostic value for serum ESR, CRP, and D-dimer (AUC in the 0.6–0.9 range) and a moderate diagnostic value for synovial fluid WBC and PMN% (AUC 0.7–0.93) [12,15,16,17,18,21,23]. The gene discussed is CRP; the disease is juvenile polyposis syndrome.