Three variables associated with a reduced likelihood of positive RD-LDL-C: diabetes mellitus (HR 0.17 [0.06, 0.51], p = 0.002), supervised in-hospital training during Phase 2 CRP (HR 0.28 [0.09, 0.86], p = 0.03), and higher levels of corrected basal LDL-C (HR 0.98 [0.97, 0.99] per mg/dL, p = 0.001). The gene discussed is CRP; the disease is diabetes mellitus.