Sham + VehicleUnderwent the sham procedure (no tooth pulp exposure)Treated systemically with a vehicle control solutionDrilled (Pulp-Exposed) + VehicleUnderwent coronal pulpotomy in the left mandibular first molar (to create pulpitis).Treated systemically with the same vehicle control solutionDrilled (Pulp-Exposed) + CBDUnderwent coronal pulpotomy in the left mandibular first molarTreated systemically with 5 mg/kg of CBDDrilled (Pulp-Exposed) + β-CaryophylleneUnderwent coronal pulpotomy in the left mandibular first molarTreated systemically with 30 mg/kg of β-CP. Here, OPN1SW is linked to pulpitis.