Sekiguchi et al. found that levels above 9.8 U/mL were predictive of new-onset AF in postmenopausal women, while Arbault-Biton et al. demonstrated that CA125 correlated with CHA2DS2-VASc scores and could detect AF of <48 h duration as accurately as NT-proBNP [94,95]. The gene discussed is NPPB; the disease is atrial fibrillation.