NPPB and ST Elevation Myocardial Infarction: In ST-elevation myocardial infarction (STEMI), Falcão et al. identified a CA125 cut-off of 12.45 U/mL with prognostic accuracy comparable to NT-proBNP based on Killip classification, and Yndigegn et al. confirmed that CA125 predicts six-week mortality, as well as left ventricular dysfunction and remodeling at one year post-ACS [91,92].