AST targets several molecular pathways in tumor therapy, including P13K/Akt, nuclear factor kappa-B (NF-κB), Nrf2, peroxisome proliferator-activated receptor γ (PPARγ), Bcl2-Associated X Protein (Bax)/Bcl-2, pontin, ERK, c-Jun N-terminal kinase (JNK), Signal transducer and activator of transcription 3 (STAT3), and Mitogen-activated protein kinase (MAPK). The gene discussed is NFE2L2; the disease is neoplasm.