A significant association between TEWL measured on the forearm and the AGT M235T polymorphism was found, where AD women—carriers of the MM genotype—had a median 25 g/m2/h and a range of 4–61 g/m2/h; female patients with the MT genotype had 10 g/m2/h, with a range of 0.3–39 g/m2/h; and female patients with the TT genotype had 5 g/m2/h, with a range of 3–40 g/m2/h, p = 0.003; see Table 4. This evidence concerns the gene AGT and Alzheimer disease.