LTA and Alzheimer disease: A family history of diabetes mellitus was associated with the TNF-β Fok1 polymorphism, where the B1 allele was more frequent in AD men with a positive family history of diabetes mellitus [OR = 5.667, 95% CI 1.30–24.53, p = 0.02, sensitivity 0.85, specificity 0.50, power test 0.570].