ADIPOQ and adiponectin deficiency: -Associated with increased risk of hypoadiponectinemia, the mean serum adiponectin levels lower in subjects with GG (4.99 ug/mL, p = 0.007 for controls; 4.54 μg/mL, p = 0.017 in diabetics) and TG (6.00 μg/mL, p = 0.001 for controls; 4.75 μg/mL, p < 0.0001 in diabetics) compared to TT (7.31 μg/mL in controls; 6.03 μg/mL for diabetics); frequency of G allele was significantly higher in T2DM patients (p < 0.001)