To assess TIGD1 gene expression across TCGA tumors, we utilized the TIMER2.0 database, revealing significant differences between cancer and normal tissues in BLCA, CHOL, ESCA, GBM, HNSC, KICH, KIRP, LIHC, LUAD, LUSC, PCPG, PRAD, READ, SKCM, STAD, THCA, and UCEC. The gene discussed is TIGD1; the disease is cancer.