The neuro-functional recovery observed after stroke was enhanced by miR-17-92-cluster-enriched MSC exosomes, which may be linked to increased axonal extension and myelination [43], and mediated through the activation of the PTEN-mediated PI3K/Akt/mTOR pathway [43] or via PI3K/AKT/VEGFA [45]. The gene discussed is PTEN; the disease is stroke disorder.