SOD1 and amyotrophic lateral sclerosis: Another study investigated the deregulated expression of a panel of lncRNAs (linc-Enc1, linc–Brn1a, linc–Brn1b, linc-p21, Hottip, Tug1, Eldrr, and Fendrr) in a murine familial model of ALS (the SOD1-G93A mouse) in presymptomatic (8 weeks) and symptomatic (18 weeks) phases of the disease [116].