Another onco-miRNA, such as miR142, may act as a suppressor of the pro-apoptotic gene TP53INP1. In contrast, other relevant downregulated tumor-suppressor miRNAs, like miR141 and miR200c, have been described in in Mycosis Fungoides (MF) tumor stage as members of the Notch pathway, activated by upregulation of Jagged1 [301,302]. The gene discussed is JAG1; the disease is neoplasm.