Other non-hematological malignancies are also ALK positive, such as metastatic non-small-cell lung cancer metastatic carcinoma [146,147], inflammatory myofibroblastic tumors, ALK-positive histiocytosis [148], Merkel cell carcinoma [149], ALK-positive large cell neuroendocrine carcinoma [150], primary/metastatic cutaneous melanomas [151], Spitz tumors with ALK fusions [152], ALK rearranged renal cell carcinoma [153], epithelioid inflammatory myofibroblastic sarcoma [154] and almost all cases of pediatric spindle cell/sclerosing rhabdomyosarcoma [155,156]. The gene discussed is ALK; the disease is renal cell carcinoma.