Alu RNA induces epithelial-to-mesenchymal transition in colorectal cancer via NLRP3 inflammasome activation and IL-1β release [122], while BC200 promotes EBV-associated nasopharyngeal carcinoma by sequestering miR-6834-5p to upregulate thymidylate synthase [123]. The gene discussed is IL1B; the disease is colorectal cancer.