JUN and cancer: In fact, transcriptional comparison with a gland tumor model had revealed recurring genes involved in the EMT process, cell migration, focal adhesion, and integrin complex formation [42], as well as the deregulation of axon guidance molecules, fibrosis, the IL8 pathway, and genetic targets of cancer-associated TFs such as NFKB1, STAT3, RELA, JUN, and HIF1A (Appendix A).