NFKB1 and rheumatoid arthritis: The impact on the IL-17 cytokine secretion is one of the important directions in modifying the inflammatory process in RA, as this cytokine, through the activation of IL-17RA, transmits a signal via the Act1-TRAF6 pathway, leading to the activation of NF-κB, MAPK, and PI3K pathways [157,174].