The presence of miR-29a-3p and miR-93-5p in G-MDSC exosomes can influence another aspect of the RA autoimmunity by reducing the elevated Th1 and Th17 levels in RA, which is accompanied by a decrease in inflammatory cytokines IFN-γ and IL-17A [197]. This evidence concerns the gene IFNG and rheumatoid arthritis.