The variables included in the model were rs4410871, rs9936833, rs3132680, and rs3823417, along with clinical and demographic factors such as a family history of IBD, BMI, sex, current anti-TNF therapy, smoking status, disease duration, ESRs, European ancestry (EUR), African ancestry (AFR), Amerindian ancestry (AMR), CRP, age, white blood cell count, hemoglobin levels, platelet count, and albumin level. The gene discussed is CRP; the disease is inflammatory bowel disease.