WEE1 and cancer: While a study reported low WEE1 expression in breast tumors, which was independent of tumor grade in comparison to normal tissue pathology based on the analysis of the data in in the Oncomine cancer microarray database [59], another study with 8636 primary breast cancers, including 1847 TNBC, gathered from 36 public gene expression data sets [60] showed that in TNBC, high-level WEE1 gene expression was associated with poor prognosis [61].