HIV infection correlates with increased levels of systemic inflammatory mediators, such as IL-6 and interferon-gamma-inducible protein 10 (IP-10), also known as C-X-C motif chemokine ligand 10 (CXCL10), along with chronic immune activation, which is evidenced by the persistent activation of platelets, monocytes, and T cells [7]. The gene discussed is CXCL10; the disease is HIV infectious disease.