In one of them, basal KLCs were obtained from iPSCs of patients with ARCI associated with mutations in the TGM1 c.765delT or PNPLA1 c.736C>T genes and with a form of syndromic ichthyosis trichothiodystrophy (TTD) caused by the c.335G>A mutation in the ERCC2 gene. Here, TGM1 is linked to autosomal recessive congenital ichthyosis.