The four suggested biomarkers from our investigation, which positively correlate with CD8+ T-cell infiltration and negatively correlate with TGFB2 methylation in PDAC, have shown associations with prognosis across cancers including: breast cancer [52], bladder cancer [53] and head and neck squamous cell carcinoma [54]. Here, TGFB2 is linked to head and neck squamous cell carcinoma.